The cost of obtaining NMPA certification for medical devices in China can vary widely based on several factors:

1. Device Type and Complexity: Costs increase with device classification (Class I, II, III) and complexity. Higher-class devices typically require more extensive documentation and testing.

2. Clinical Trials: If required, clinical trials can significantly increase costs, including study design, execution, and data analysis.

3. Regulatory Fees: Application fees and charges for NMPA reviews. These fees can range from a few thousand to several tens of thousands of RMB.

4. Local Representation: Fees for appointing a local agent or distributor in China.

5. Testing and Certification: Costs for testing and certification by recognized Chinese laboratories, which may include safety, efficacy, and quality tests.

6. Translation and Documentation: Costs associated with translating documentation and labels into Chinese.

7. Quality Management System Compliance: Costs related to achieving and maintaining ISO 13485 certification if not already in place.

Overall, the total cost can range from RMB 50,000 to over RMB 500,000, depending on the device and specific requirements.